Search Publications
- Jakab F, Mayer Á, Hoffmann A, Hidvégi M (2000): First clinical data of a natural immunomodulator in colorectal cancer. Hepatogastroenterology. 47:393-5.
- Hidvégi M, Moldvay J, Lapis K, Ajkay Z (2003): Fermentált búzacsíra tartalmú készítmény alkalmazásakor javul a tüdőrákos betegek életminősége. Medicus Anonymus (Pulmono). 1:13-4.
- Szende B, Rásó E, Hidvégi M, Tömösközi-Farkas R, Paku S, Prónai L, Bocsi J, Lapis K (1998): Egy új, szubszituált benzokinon tartalmú antimetasztatikus készítmény. Orv Hetil. 139(48):2893-7.
- Nichelatti M, Hidvégi M (2002): Experimental and clinical results with Avemar (a dried extract from fermented weath germ) in animal cancer models and in cancer patients. Nőgyógyászati Onkológia. 7:40-1.
Papers on Avemar. Collected by Máté Hidvégi PhD
Abdelbaky MS (2012): Effect of raw and fermented wheat germ on oxidative and immune stress induced by carbon tetrachloride
(CCl4) hepatic toxicity in rats. MBSE. 2012, 26, 617-640.
(CCl4) hepatic toxicity in rats. MBSE. 2012, 26, 617-640.
Abdelmonem M, Kassem SH, Gabr H, Shaheen AA, Aboushousha T (2015): Avemar and Echinacea extracts enhance mobilization and homing of CD34+ stem cells in rats with acute myocardial infarction. Stem Cell Research & Therapy. 6:172 (17 pages).
Abdelmonem M (2016): Role of some natural products in mobilization of stem cells in rats with acute myocardial infarction. Thesis. Submitted for partial fulfillment of the master degree in Pharmaceutical Sciences (Biochemistry). Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Alfarouk KO, Alhoufie STS, Hifny A, Schwartz L, Alqahtani AS, Ahmed SBM, Alqahtani AM, Alqahtani SS, Muddathir AK, Ali H, Bashir AHH, Ibrahim ME, Greco MR, Cardone RA, Harguindey S, Reshkin SJ (2021): Of mitochondrion and COVID-19. J Enzyme Inhibition Med Chem. 36:1, 1258-1267.
Anonymous (2003): Case studies with Avemar. Medpro-International publication. Scherpenzeel (Netherlands).
Anonymous (2017): Chemotherapy. LifeExtension’s Health Protocols. Fort Lauderdale, FL.
Arshad MS, Kwon J-H, Anjum FM, Sohaib M, Saeed F, Imran M, Amjad Z, Nadeem M, Hussain S (2017): Wheat antioxidants, their role in bakery industry, and health perspective. In: Wheat improvement, management and utilization. Eds. R. Wanyera, J. Owuoche. InTech, Rijeka, Croatia, pp. 365-81.
Bagó-Horváth Z, Forstner B, Kalipciyan M, Bedeir A, Grusch M, Komina O, Wesierska-Gadek J, Szekeres T, Hidvégi M, Mader RM (2011): Favourable anti-cancer activity of fermented wheat germ freeze-dried extract (Avemar lyophilisate) in triple-negative breast cancer cells. Ann Oncol. 22(S2):ii54-7.
Bagó-Horváth Z, Teichmann M, Forstner B, Komina O, Bedeir A, Wesierska-Gadek J, Grusch M, Szekeres T, Krupitza G, Mader RM (2011): Avemar, a lyophilised fermented wheat germ extract inhibits breast cancer cell proliferation and invasion in vitro. Poster presentation at the ESMO 2011. European Cancer Congress. Stockholm, Sweden, 23 Sep – 27 Sep, 2011.
Baig MH, Adil M, Khan R, Dhadi S, Ahmad K, Rabbani G, Bashir T, Imran MA, Husain FM, Lee EJ, Kamal MA, Choi I (2019): Enzyme targeting strategies for prevention and treatment of cancer: Implications for cancer therapy. Semin Cancer Biol. 56: 1-11. doi:https://doi.org/10.1016/j.semcancer.2017.12.003
Bakalova R, Lazarova D, Sumiyoshi A, Shibata S, Zhelev Z, Nikolova B, Semkova S, Vlaykova T, Aoki I, Higashi T (2023): Redox-cycling “mitocans” as effective new developments in anticancer therapy. Int J Mol Sci. 24, 8435. (23 pages).
Bálint G, Apáthy Á, Gaál M, Telekes A, Resetár Á, Blazsó G, Falkay G, Szende B, Paksy A, Ehrenfeld M, Shoenfeld Y, Hidvégi M (2006): Effect of Avemar – a fermented wheat germ extract – on rheumatoid arthritis. Preliminary data. Clin Exp Rheumatol. 24:325-8.
Bar-Sela G, Cohen M, Ben-Arye E, Epelbaum R (2015): The medical use of wheatgrass: Review of the gap between basic and clinical applications. Mini Rev Med Chem. 15:1002-10.
Barabás J, Németh Z (2006): A Magyar Arc-, Állcsont- és Szájsebészeti Társaság állásfoglalása szájüregi daganatos betegek Avemarral történő szupportív kezelésének indokoltságáról. Orv Hetil. 147(35):1709-11.
Barakat H, Khalil FA, Khalifa FK, Hessin MM (2011): Biochemical role of fermented wheat germ on liver and kidney functions alteration induced by chlorpyrifos in rats. Afr J Biol Sci. 7(1):45-60.
Barisone GA, Ma Y, Abuhay MW, O’Donnell RT, Lundeberg K, Gowda S, Murphy W, Tuscano JM (2017): A protein extract from fermented wheat germ promotes NK cell-mediated lymphoma eradication in mouse xenografts. J ImmunoTherapy Cancer. 5(Suppl 2):P306.
Barisone GA, O’Donnell RT, Ma Y, Abuhay MW, Lundeberg K, Gowda S, Tuscano JM (2018): A purified, fermented, extract of Triticum aestivum has lymphomacidal activity mediated via natural killer cell activation. PLoS ONE. 13(1).
Bau LA (2006): Das Transketolase-like-1 Protein (TKTL1) im Mammakarzinom. Dissertation. Medizinischen Fakultät der Albert-Ludwigs-Universität Freiburg im Breisgau.
Bencze G, Bencze S, Rivera KD, Watson JD, Hidvégi M, Orfi L, Tonks NK, Pappin DJ (2020): Mito‑oncology agent: fermented extract suppresses the Warburg effect, restores oxidative mitochondrial activity, and inhibits in vivo tumor growth. Sci Rep. 10: 14174. doi:10.1038/s41598-020-71118-3
Bender A (2010): Suzanne Dixon, MPH, RD talks about the dietary supplement Avemar. American Institute for Cancer Research. (About.com is part of the New York Times Company).
Bin X, Ying D (2011): Present situation and trends of wheat germ industrialization developing. Transactions of the CSAE. 27(S2):341-5. (in Chinese with English abstract).
BioAthens (2014): ΤΟ ΦΥΤΡΟ ΣΙΤΑΡΙΟΥ ΠΟΥ ΕΧΕΙ ΥΠΟΣΤΕΙ ΖΥΜΩΣΗ ΣΚΟΤΩΝΕΙ ΤΟΝ ΚΑΡΚΙΝΟ. http://www.bioathens.com. Available at: http://www.bioathens.com/to-fitro-sitariou-pou-exei-ipostei-zimosh-skotonei-ton-karkino/
Bishop KD (2012): Glioblastoma. Alternative cancer treatment research report.
Bogár Z (2017): Krebsbekaempfung – Produkt aus Gottes Muehle.
Boros LG, Lapis K, Szende B, Tömösközi-Farkas R, Balogh Á, Boren J, Marin S, Cascante M, Hidvégi M (2001): Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells. Pancreas. 23(2):141–7.
Boros LG, Lee W-NP, Go VLW (2002): A metabolic hypothesis of cell growth and death in pancreatic cancer. Pancreas. 24(1):26-33.
Boros LG, Hidvégi M (2002): Az Avemar hatásmódja (4) – daganatok anyagcseréjének módosítása. Nőgyógyászati Onkológia. 7:239-41.
Boros LG, Cascante M, Lee W-NP (2002): Metabolic profiling of cell growth and death in cancer: applications in drug discovery. Drug Discovery Today. 7(6):18-26.
Boros LG, Brackett DJ, Harrigan GG (2003): Metabolic biomarker and kinase drug target discovery in cancer using stable isotope-based dynamic metabolic profiling (SIDMAP). Current Cancer Drug Targets. 3:447-55.
Boros LG, Nichelatti M, Shoenfeld Y, Shoenfeld Y (2005): Fermented wheat germ extract (Avemar) in the treatment of cancer and autoimmune diseases. Ann N Y Acad Sci. 1051:529-42.
Boros LG (2005): Metabolic targeted therapy of cancer: current tracer technologies and future drug design strategies in the old metabolic network. Metabolomics. 1(1):11-15.
Boros LG (2005): Metabolic profile of inflammatory breast cancer: aiding diagnosis and treatment. UCLA School of Medicine.
Brambilla D, Mancuso C, Scuderi MR, Bosco P, Cantarella G, Lempereur L, Benedetto GD, Pezzino S, Bernardini R (2008): The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile. Nutr J. 7:29 (9 pages).
Brandolini A, Hidalgo A (2012): Wheat germ: not only a by-product. Int J Food Sci Nutr. 63 (Suppl 1):71-4.
Mercédesz B-PJ (2022): Potenciálisan védő hatású anyagok alkalmazhatósága mikotoxinok által károsított bélbarrier épségének fenntartására in vitro modellben. PhD értekezés. Állatorvostudományi Egyetem, Állatorvostudományi Doktori Iskola, Budapest. . (119 Pages).
Buta S, Al-Ibrahim AS (2021): Enriching Arabic bread wheat germ fermented by baker’s yeast. Al-Baath University Journal. 43(6): 45-64, 2021.
Cascante M, Boros LG, Comín-Anduix B, Atauri P de, Centelles JJ, Lee W-NP (2002): Metabolic control analysis in drug discovery and disease. Nat Biotechnol. 20:243-9.
Cascio S (2013): Germe de blé fermenté, miracle santé à travers les âges. Medicatrix, Embourg (Belgique).
Cascio S (2013): The discovery of Avemar. An interview with Mate Hidvegi.
Cassileth BR, Yeung KS, Gubili J (2007): Wheat germ extract. In: Herb-drug interactions in oncology. Cancer Center, New York NY and People’s Medical Publishing House–USA, Shelton CT, p. 694-6.
Ceccherini E, Rinaldini M, Bignardi B, Senesi S, Caloni V (2002): Considerazioni sulle terapie non convenzionali dei tumori e sulla possibile attività antitumorale di alcune sostanze naturali. Oncology & Hematology Review. 4(2):109-120.
Challem J (2012): Fermented wheat germ extract – An adjunct treatment for cancer? Alternat Complement Therapies. 18(4):199-201.
Coghill R, Baghurst R (2004): An investigation into the effects of high dilution quinones on peripheral blood leukaemic lymphocyte metabolism. http://cwl2004.powerwatch.org.uk/. Available at: http://cwl2004.powerwatch.org.uk/programme/posters/day1-baghurstcoghill2.pdf
Cold Spring Harbor Laboratory (2013): Characterization of novel cancer therapeutics. Characterization of novel kinase inhibitors. (Excerpts from the 2009, 2011 and 2012 Annual Reports of CSHL. Cold Spring Harbor, NY).
Comín-Anduix B, Boros LG, Marin S, Boren J, Callol-Massot C, Centelles JJ, Torres JL, Agell N, Bassilian S, Cascante M (2002): Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells. J Biol Chem. 277(48):46408-14.
Conners CMA, Coghill RW (2004): Effect of high dilution quinones on O2 uptake by peripheral blood lymphocytes: a polarigraphic study. http://cwl2004.powerwatch.org.uk/. Available at: http://cwl2004.powerwatch.org.uk/programme/posters/day4-connerscoghill.pdf
Coy JF, Dressler D, Wilde J, Schubert P (2005): Mutations in the Transketolase-like gene TKTL1: Clinical implications for neurodegenerative diseases, diabetes and cancer. Clin Lab. 51:257-73.
Darus NM (2013): Avemar Granulate as dietary food / special purpose food for cancer. Reviewed by: Datin Dr Rugayah Bakri. Health Technology Assessment Section (MaHTAS), Medical Development Division, Ministry of Health Malaysia, Putrajaya, Malaysia.
De Monaco A, D’Orta A, Del Buono A (2014): Evolution of bread-making quality in wheat: implications about cancer prevention. World Cancer Res J. 1(2): e214.
De Petris M (2012): Cibo e malattie autoimmuni. http://nutrizioneconsapevole.altervista.org/. Available at: http://nutrizioneconsapevole.altervista.org/cibo-e-malattie-autoimmuni-dott-ssa-michela-de-petris
Demidov LV, Manziuk LV, Kharkevitch GY, Pirogova NA, Artamonova EV (2008): Adjuvant fermented wheat germ extract (Avemar) nutraceutical improves survival of high-risk skin melanoma patients: a randomized, pilot, phase II clinical study with a 7-year follow-up. Cancer Biother Radiopharm. 23(4):477-82.
Di Napoli R, Balzano N, Mascolo A, Cimmino C, Vitiello A, Zovi A, Capuano A, Boccellino M (2023): What is the role of nutraceutical products in cancer patients? A systematic review of randomized clinical trials. Nutrients. 15: 3249.
Du K, Tian S, Chen H, Gao S, Dong X, Yan F (2022): Application of enzymes in the preparation of wheat germ polypeptides and their biological activities. Front Nutr. 9: 943950. (11 pages). doi:10.3389/fnut.2022.943950
Editorial (2008): In pursuit of options. Norman deLeuze fuels the hunt for a nontoxic cure for lymphoma. Synthesis. (University of California Davis Cancer Center). 11(1):19-21.
Editorial (2014): A gift that keeps on giving. Endowed professorship seeks lymphoma cure. Synthesis. (University of California Davis Comprehensive Cancer Center). 17(2):24-5.
Ehrenfeld M, Blank M, Shoenfeld Y, Hidvégi M (2001): Avemar (a new benzoquinone-containing natural product) administration interferes with the Th2 response in experimental SLE and promotes amelioration of the disease. Lupus. 10:622-7.
Ehrlich SD (2012): Bone cancer. University of Maryland Medical Center. Complementary and Alternative Medicine Guide. Baltimore, MD.
Eich KPJ, Karaaslan F, Pfetzer N, Germer CT, Otto C (2011): Induzieren zelltoxische Benzochinone den anti-Tumoreffekt von Avemar? Universitätsklinikum Würzburg, Germany.
Eich KPJ (2013): Untersuchungen in vitro zur therapeutischen Wertigkeit von 2,6-Dimethoxy-1,4-benzochinonen im Supportivprodukt Avemar. Inaugural Dissertation zur Erlangung der Doktorwürde der Medizinischen Fakultät der Julius Maximilians Universität zu Würzburg.
El-Batal AI, Omayma AR, Eman N, Effat SI (2012): Promising antitumor activity of fermented wheat germ extract in combination with selenium nanoparticles. Int J Pharm Sci Health Care. 6(2):1. (22 pages).
Ellakany H, El-Sayed AE-H, Soliman F, Elbestawy A (2017): The effect of fermented wheat germ extract on biochemical, physiological and performance parameters of broiler chickens. Alexandria Journal of Veterinary Sciences. 55(2): 91-7.
Bayat E, Moosavi-Nasab M, Fazaeli M, Majdinasab M, Mirzapour-Kouhdasht A, Garcia-Vaquero M (2022): Wheat Germ Fermentation with Saccharomyces cerevisiae and Lactobacillus plantarum: Process Optimization for Enhanced Composition and Antioxidant Properties In Vitro. Foods. (12 pages).
Ervolino F (2009): Curing cancer’s sweet tooth.
Fajka-Boja R, Hidvégi M, Shoenfeld Y, Ion G, Demydenko D, Tömösközi-Farkas R, Vizler C, Telekes A, Resetár Á, Monostori É (2002): Fermented wheat germ extract induces apoptosis and downregulation of major histocompatibility complex class I proteins in tumor T and B cell lines. Int J Oncol. 20:563-70.
Farkas E (2004): Áttekintés az Avemar onkológiában betöltött szerepéről. Magy Belorv Arch. 57:4-9.
Farkas E (2005): Szupportív kezelés fermentált búzacsíra-kivonattal colorectalis carcinomában. Orv Hetil. 146(37):1925-31.
Farkas E (2006): Fermentált búzacsíra kivonat (Avemar) alkalmazásának lehetőségei a családorvosi gyakorlatba. Medicus Universalis. 39(1):19-31. Available at: http://hidvegimate.hu/download.php?id=101
Flowers CR, Seidenfeld J, Bow EJ, Karten C, Gleason C, Hawley DK, Kuderer NM, Langston AA, Marr KA, Rolston KVI, Ramsey SD (2012): Antimicrobial prophylaxis and outpatient management of fever and neutropenia in adults treated for malignancy: American Society of Clinical Oncology Clinical Practice Guideline. http://www.asco.org/. Available at: http://www.asco.org/sites/www.asco.org/files/fn_adult_guideline.pdf
Fog- és Szájbetegségek Szakmai Kollégiuma (2008): Állásfoglalás a szájüregi daganatos betegek Avemarral történő szupportív kezelésének indokoltságáról. Budapest. Available at: http://hidvegimate.hu/download.php?id=79
Gan R-Y, Li H-B, Gunaratne A, Sui Z-Q, Corke H (2017): Effects of fermented edible seeds and their products on human health: Bioactive components and bioactivities. Comprehensive Reviews in Food Science and Food Safety. doi:10.1111/1541-4337.12257
Garami M, Schuler D, Babosa M, Borgulya G, Hauser P, Müller J, Paksy A, Szabó E, Hidvégi M, Fekete G (2004): Fermented wheat germ extract reduces chemotherapy-induced febrile neutropenia in pediatric cancer patients. J Pediatr Hematol Oncol. 26(10):631-5.
Giessrigl B (2011): New approaches in the targeting of cell cycle, cell death and cancer progression: Models for improved tumor therapy. Dissertation (Doktor der Naturwissenschaften). Universität Wien.
Grimm M, Cetindis M, Lehmann M, Biegner T, Munz A, Teriete P, Kraut W, Reinert S (2014): Association of cancer metabolism-related proteins with oral carcinogenesis – indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma? J Translational Med. 12:208.
Hahlbrock T (2016): Das onkologische Supportivprodukt Avemar: Untersuchungen zum antiproliferativen und antimetabolischen Effekt an humanen gastrointestinalen Tumorzellen. naugural-Dissertation zur Erlangung der Doktorwürde der Medizinischen Fakultät der Julius-Maximilians-Universität zu Würzburg.
Hajtó T, Adámy A, Langmár Z, Kirsch A, Ábrahám L, Perjési P, Németh P (2013): Enhanced effectiveness of conventional oncotherapy with plant immunomodulators: Overview of recent advances. Advancement Medicinal Plant Res. 1(3):56-65.
Hajtó T, Kirsch A (2013): Case reports of cancer patients with hepatic metastases treated by standardized plant immunomodulatory preparations. J Cancer Res Updates. 2(1):1-9.
Hajtó T, Adámy A, Baranyai L, Langmár Z, Kirsch A, Kuzma M, Ábrahám L, Perjési P (2014): Can standardized plant extracts induce complete remission in patients with metastatic tumors? Altern Integ Med. 3(3):161.
Hardy ML (2008): Dietary supplement use in cancer care: help or harm. Hematol Oncol Clin N Am. 22:581–617.
Harguindey S, Reshkin SJ, Alfarouk KO (2023): The prime and integral cause of cancer in the post-Warburg era. Cancers. 2023, 15(2), 540. doi:https://doi.org/10.3390/cancers15020540
Harrigan GG, Brackett DJ, Boros LG (2005): Medicinal chemistry, metabolic profiling and drug target discovery: A role for metabolic profiling in reverse pharmacology and chemical genetics. Mini Rev Med Chem. 5(1):13-20.
Heimbach JT, Sebestyén G, Semjén G, Kennepohl E (2007): Safety studies regarding a standardized extract of fermented wheat germ. Int J Toxicol. 26:253-9.
Herring J (2012): Three proven ways to survive cancer (and chemotherapy). Natural Health Dossier. August issue 28. (10 pages).
Hidvégi M, Rásó E, Tömösközi-Farkas R, Paku S, Lapis K, Szende B (1998): Effect of Avemar and Avemar + Vitamin C on tumor growth and metastasis in experimental animals. Anticancer Res. 18:2353-8.
Hidvégi M, Rásó E, Tömösközi-Farkas R, Lapis K, Szende B (1999): Effect of MSC on the immune response of mice. Immunopharmacology. 41:183-6.
Hidvégi M, Rásó E, Tömösközi-Farkas R, Szende B, Paku S, Prónai L, Bocsi J, Lapis K (1999): MSC, a new benzoquinone-containing natural product with antimetastatic effect. Cancer Biother Radiopharm. 14(4):277-89.
Hidvégi M, Moldvay J, Lapis K, Ajkay Z (2003): Fermentált búzacsíra tartalmú készítmény alkalmazásakor javul a tüdőrákos betegek életminősége. Medicus Anonymus (Pulmono). 1:13-4.
Hidvégi M (2009): Fermented wheat germ extract (Avemar). Lecture presented for the Consortium of Academic Health Centers for Integrative Medicine (CAHCIM) March 27, 2009 Oncology Interest Group Meeting.
Horváth J, Olajos J (2020): Klinikai táplálásterápia az onkológiában. Ápolásügy. 34(3), 15-16. 2020.
Hübner J (2014): Komplementärmedizin für Krebspatienten. Techniker Krankenkasse, Hamburg.
Hung H-S, Bau D-T, Yeh C-A, Kung M-L (2019): Evaluation of cellular uptake mechanisms for AuNP-collagen-Avemar nanocarrier on transformed and non-transformed cell lines. Colloids and Surfaces A. (2019) 580:123791.
Illmer C, Madlener S, Horváth Z, Saiko P, Losert A, Herbacek I, Grusch M, Krupitza G, Fritzer-Szekeres M, Szekeres T (2005): Immunologic and biochemical effects of the fermented wheat germ extract Avemar. Exp Biol Med. (Maywood). 230:144-9.
Imir NG, Aydemir E, Şimşek E (2018): Mechanism of the anti-angiogenic effect of Avemar on tumor cells. Oncol Lett. 15(2):2673-2678.
Issels blog (2016): Wheat germ extract shows potent anti-cancer activity. The Issels News Blog. November 22, 2016.
Iyer A, Brown L (2009): Fermented wheat germ extract (Avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats. Evid Based Complement Alternat Med. 2011:508957.
Jakab F, Mayer Á, Hoffmann A, Hidvégi M (2000): First clinical data of a natural immunomodulator in colorectal cancer. Hepatogastroenterology. 47:393-5.
Jakab F, Shoenfeld Y, Balogh Á, Nichelatti M, Hoffmann A, Kahán Z, Lapis K, Mayer Á, Sápy P, Szetntpétery F, Telekes A, Thurzó L, Vágvölgyi A, Hidvégi M (2003): A medical nutriment has supportive value in the treatment of colorectal cancer. Br J Cancer. 89(3):465-9.
Jeong H-Y, Choi Y-S, Lee J-K, Lee B-J, Kim W-K, Kang H (2017): Anti-inflammatory activity of citric acid-treated wheat germ extract in lipopolysaccharide-stimulated macrophages. Nutrients. 2017, 9(7), 730. (12 pages).
Jing X, Dong Y (2009): Study on 2,6-DMBQ from fermented wheat germ. Food Sci Technol (Chinese). 2009-06.
Johanning GL, Wang-Johanning F (2007): Efficacy of a medical nutriment in the treatment of cancer. Altern Ther Health Med. 13(2):56-65.
Johl J (2014): Cancer health benefits of fermented wheat germ. Diablo Valley Oncology & Hematology. San Francisco Bay Area Oncology.
Jribi S, Chabbouh M, Sassi K, Sfayhi D, Marzougut S, Amara H, Debbabi H (2018): La germination, un bioprocédé au service de l’industrie agro-alimentaire? Journal of New Sciences, Agriculture and Biotechnology. 57(5): 3725-37.
Judson PL, Sawah EA, Marchion DC, Xiong Y, Bicaku E, Zgheib NB, Chon HS, Stickles XB, Hakam A, Wenham RM, Apte SM, Gonzalez-Bosquet J, Chen D-T, Lancaster JM (2012): Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity. Int J Gynecol Cancer. 22(6):960-7.
Kalisch A, Horneber M, CAM-Cancer Consortium (2013): Fermented wheat germ extract. [online document]. August 21, 2013.
Kalisch A, Horneber M, CAM-Cancer Consortium (2019): Fermented wheat germ extract. http://cam-cancer.org/. Available at: http://cam-cancer.org/en/fermented-wheat-germ-extract
Karaaslan F (2012): Untersuchungen zum antikanzerogenen Potential von Benzochinonen: Oxidativer Stress als Auslöser zelltoxischer Effekte. Inaugural-Dissertation zur Erlangung der Doktorwürde der Medizinischen Fakultät der Julius-Maximilians-Universität zu Würzburg. Würzburg, pp. 93.
Katz D (2011): Six habits that can add years to your life. Huffington Post.
Kaur B, Kumar B, Sirhindi G, Guleria N, Kaur J (2023): Phenolic biotransformations in wheatgrass juice after primary and secondary fermentation. Foods. 12, 1624.
Kenner D (2006): Avemar – a functional food with proven anti-cancer effect. Townsend Letter. August/September issue:96-100.
Kesika P, Sivamaruthi BS, Chaiyasut C (2020): Health promoting effects of fermented foods against cancer: an updated concise review. Food Sci. Technol, Campinas. (9 pages). doi:https://doi.org/10.1590/fst.18220
Khanna D, Sethi G, Ahn KS, Pandey MK, Kunnumakkara AB, Sung B, Aggarwal A, Aggarwal BB (2007): Natural products as a gold mine for arthritis treatment. Curr Opin Pharmacol. 7:344–51.
Kim M-H, Jo S-H, Ha K-S, Song J-H, Jang H-D, Kwon Y-I (2010): Antimicrobial activities of 1,4-benzoquinones and wheat germ extract. J Microbiol Biotechnol. 20:1204-09.
Kim YS, Milner JA (2011): Bioactive food components and cancer-specific metabonomic profiles. J Biomed Biotechnol. 2011:721213 (9 pages)
Klein P, Tyrlikova I, Zuccoli G, Tyrlik A, Maroon JC (2020): Treatment of glioblastoma multiforme with “classic” 4:1 ketogenic diet total meal replacement. Cancer Metab. 8, 24. doi:https://doi.org/10.1186/s40170-020-00230-9
Koltai T (2021): Where do we stand with fermented wheat grain extract for cancer treatment: lights and shadow? Preprint. August 2021. doi:10.13140/RG.2.2.25241.54887
Kósa E, Jakab L, Nagy G (2007): Effect of a prebioticum “IMMUNOVET-HBM™” on the health status and production of Hungarian turkey flocks. In: Turkey production: Current challenges. Ed. H. M. Hafez. Mensch Buch Verlag, Berlin, pp. 174-82.
La Marca M, Beffy P, Pugliese A, Longo V (2013): Fermented wheat powder induces the antioxidant and detoxifying system in primary rat hepatocytes. Plos One. 8:12 (9 pages).
Ladas EJ (2018): Integrative Medicine in Childhood Cancer. J Altern Compl Med. 24(9-10): 910-15.
Lai JN, Chen PC, Wang JD, Wu TCJ, Chung V (2015): Integrative gynecology and women’s healthcare. Evid-based Compl Altern Med. Article ID 852615.
Langbein S, Zerilli M, Hausen A, Staiger W, Rensch-Boschert K, Lukan N, Popa J, Ternullo MP, Steidler A, Weiss C, Grobholz R, Willeke F, Alken P, Stassi G, Schubert P, Coy JF (2006): Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted. Br J Cancer. 94:578-85.
Lankford S (2014): Avemar for cancer support. An interview with James LaValle. Health Quest Podcast.
Lee C, Park G-H, Lee J-W, Jang J-H (2015): Protective effect of wheat bran extract against β-amyloid-induced cell death and memory impairment. The Korea Journal of Herbology. 30(1): 67-75.
Lee SN, Park H, Lee KE (2005): Cytotoxic activities of fermented wheat germ extract on human gastric carcinoma cells by induction of apoptosis. J Clin Oncol. 23(16):4254.
Liaqat H, Jeong E, Kim KJ, Kim JY (2020): Effect of wheat germ on metabolic markers: a systematic review and meta-analysis of randomized controlled trials. Food Sci Biotechnol. 29(6):739-49.
Liu J-C, Shen W-C, Shih T-C, Tsai C-W, Chang W-S, Cho D-Y, Tsai C-H, Bau D-T (2015): The current progress and future prospects of personalized radiogenomic cancer study. BioMedicine. Vol. 5, No. 1, Article 2, Pages 11-18.
Losso JN, Bawadi HA (2005): Hypoxia inducible factor pathways as targets for functional foods. J Agric Food Chem. 53:3751-68.
Lubrano V, Baldi S, Napoli D, Longo V (2012): Beneficial effect of Lisosan G on cultured human microvascular endothelial cells exposed to oxidised low density lipoprotein. Indian J Med Res. 136:82-8.
Mackei M, Vörösházi J, Sebők C, Neogrády Z, Mátis G, Jerzsele Á (2020): Fermented wheat germ extract as a redox modulator: Alleviating endotoxin-triggered oxidative stress in primary cultured rat hepatocytes. Oxidative Medicine and Cellular Longevity. Vol. 2020, Article ID 3181202, 9 pages. doi:https://doi.org/10.1155/2020/3181202
Magyar Klinikai Onkológiai Társaság I. Kongresszusa (2000): Az Avemar-kutatások összefoglalói. Lege Artis Medicinae. Lege Artis Medicinae. 11(1), 2001, különszám.
Marcsek Z, Kocsis Z, Jakab M, Szende B, Tompa A (2004): The efficacy of tamoxifen in estrogen receptor–positive breast cancer cells is enhanced by a medical nutriment. Cancer Biother Radiopharm. 19(6):746-53.
Mi S, Gu J, Cao X, Li Y, Xu Q, Chen W, Zhang Y (2022): Regulatory mechanism of fermented wheat germ on lipid metabolism in hyperlipidemia rats via activation of AMPK pathway. Food Sci Technol, Campinas. 42, e57222.
Milot B (2006): Treatment of cancer and autoimmune diseases with wheat germ extract. HerbClip. 050164-313. Available at: https://www.herbalgram.org/resources/herbclip/issues/bin_313/review44660/
Minamiyama Y, Takemura S, Yoshikawa T, Okada S (2003): Fermented grain products, production, properties and benefits to health. Pathophysiology. 9:221-7.
Mirmiran P, Bahadoran Z, Azizi F (2014): Functional foods-based diet as a novel dietary approach for management of type 2 diabetes and its complications: A review. World J Diabetes. 5(3): 267-81.
Mirzaei A, Khatami F, Ebrahimi M, Mousavibahar SH, Narouie B (2019): The Effect of Herbal Extracts on the Treatment and Prevention of Prostate Cancer: A Literature Review. Translational Research in Urology. 1(2):67-73 Autumn 2019.
Mishra J, Dromund J, Quazi SH, Karanki SS, Shaw JJ, Chen B, Kumar N (2013): Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis. Crit Rev Oncol Hematol. 86(3): 232-50.
Mogoș T, Dondoi C, Chelan C, Iacobini AE (2015): A review of recommended foods in the prevention of cancer. Rom J Diabetes Nutr Metab Dis. 22(2):193-200.
Morris GJ, Rosenzweig S (2006): The latest medical and complementary approaches for advanced breast cancer. Living Beyond Breast Cancer Conference. Ardmore PA, Novemer 4, 2006.
Mueller T, Jordan K, Voigt W (2011): Promising cytotoxic activity profile of fermented wheat germ extract (Avemar) in human cancer cell lines. J Exp Clin Cancer Res. 30:42. (7 pages).
Mueller T, Voigt W (2011): Fermented wheat germ extract – nutritional supplement or anticancer drug? Nutr J. 10:89. (6 pages).
Myers C, Stuber ML, Bonamer-Rheingans JI, Zeltzer LK (2005): Complementary therapies and childhood cancer. Cancer Control. 12(3):172-80.
Nagy G, Könyves L, Jurkovich V, Kovács P, Kósa E, Brydl E (2011): Effect of fermented wheat germ extract (FWGE) on shedding Salmonella infantis and immunreactions of broilers. In: Kofer J, Schobesberger H, eds. Animal hygiene and sustainable livestock production. Innovations in hygiene, nutrition and housing for healthy food from healthy animals. Tribun EU, Brno, Vol 2.
Nakaya T-ak, Umenai T, Hasegawa N, Nakai S, Matsuo T, Imanishi J (2006): Supression of murine melanoma growth by fermented grain extracts. Nihon Hokan Daitai Iryou Gakkaishi. 2:9-13.
National Cancer Institute (2013): Fermented wheat germ extract (Code C64763). NCI Thesaurus. U.S. National Institutes of Health, Bethesda, MD.
National Center for Biotechnology Information (2013): Fermented wheat germ extract. U.S. National Library of Medicine. Bethesda, MD.
Natural Standard Monograph and Susan G. Komen (2014): Fermented wheat germ extract. http://ww5.komen.org/. Available at: http://ww5.komen.org/BreastCancer/FermentedWheatGermExtract.html
Newell LF, Tuscano JM, O’Donnell RT, Ma Y (2010): Purified, fermented, extract of Triticum aestivum has significant independent lymphomacidal activity and augments the activity of rituximab. 53rd ASH Annual Meeting and Exposition. Orange County, CA.
Nichelatti M, Hidvégi M (2002): Experimental and clinical results with Avemar (a dried extract from fermented weath germ) in animal cancer models and in cancer patients. Nőgyógyászati Onkológia. 7:40-1.
Niu L-Y, Jiang S-T, Pan L-J (2013): Preparation and evaluation of antioxidant activities of peptides obtained from defatted wheat germ by fermentation. J Food Sci Technol. 50(1):53–61.
Nutt LK, Margolis SS, Jensen M, Herman CE, Dunphy WG, Rathmell JC, Kornbluth S (2005): Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of Caspase 2. Cell. 123: 89–103.
Olesova LD (2021): Perspectivity of a Biogenic Product – Juice from Wheat Sprouts in Prevention and Treatment of Diseases in the North. MEDICINE. SOCIOLOGY. PHILOSOPHY Applied Research. (2):20-24.
Otto C, Hahlbrock T, Eich KPJ, Karaaslan F, Jürgens C, Germer C-T, Wiegering A, Kämmerer U (2016): Antiproliferative and antimetabolic effects behind the anticancer property of fermented wheat germ extract. BMC Complement Altern Med. 16:160 (10 pages). doi:10.1186/s12906-016-1138-5
Park E, Kim HO, Kim G-N, Song J-H (2015): Anti-oxidant and anti-adipogenic effects of ethanol extracts from wheat germ and wheat germ fermented with Aspergillus oryzae. Prev. Nutr. Food Sci. 20(1):29-37.
Parmar G, Rurak E, Buencamino F (2016): Case study: The use of Viscum album and intravenous ascorbic acid in a Lynch syndrome patient with recurring cancer. http://www.integratedhealthclinic.com/. (11 pages). Available at: http://www.integratedhealthclinic.com/assets/caseReports/Digestive-LS-1.pdf
Patel S (2013): Fermented wheat germ extract: a dietary supplement with anticancer efficacy. Nutritional Therapy & Metabolism. 32(2): 61-7.
Pazzaglia G (2012): Avemar. In: G. Pazzaglia: Il grande libro delle terapie anticancro. Ed. R. Boriani. Sperling and Kupfer, Segrate (MI), pp. 223-227.
Pelletier M (2008): Unplugging cancer’s power supply. Anti-Aging Medical News. Summer issue:188-90.
Pfeifer B (2006): Avemar. In: Pfeifer B, Preiß J, Unger C, eds. Onkologie integrativ. Elsevier, Urban and Fischer, Munchen, p. 226-9.
Pharmindex / Tápszerindex (2007): Avemar.
Philippine Society of Medical Oncology (2013): PSMO CAM position paper. http://psmo.org.ph/. Available at: http://psmo.org.ph/tag/psmo-cam-position-paper/
Pincott I (2014): How you can keep cancer in remission? North Island MidWeek. 2014. April 29.
Pole L, Hepp N, Lerner M (2018): Beyond Conventional Cancer Therapies. Breast Cancer. Available at: https://bcct.ngo/assets/documents/BreastCancer12-10-18.pdf
Pomothy JM, Pászti-Gere E, Barna RF, Prokoly D, Jerzsele Á (2020): The Impact of Fermented Wheat Germ Extract on Porcine Epithelial Cell Line Exposed to Deoxynivalenol and T- 2 Mycotoxins. Oxidative Medicine and Cellular Longevity. Vol. 2020, Article ID 3854247, 9 pages. doi:https://doi.org/10.1155/2020/3854247
Poudel R, Bhatta M (2016): Review of nutraceuticals and functional properties of whole wheat. J Nutr Food Sci. 6: 571. (6 pages). doi:10.4172/2155-9600.1000571
Premakumari S, Haripriya S (2010): Effect of supplementation of wheat germ, wheat bran and wheat grass to subjects with specific health issues. UGC Minor Research Project no.F33-439/2007(SR). Department of Food Science and Nutrition, Avinashilingam University for Women, Coimbatore, India.
Rab L (2008): Hungarian powder. Népszabadság Online. June 19, 2008.
Radossi AL, Taromina K, Marjerrison S, Diorio CJ, Similio R, Njuguna F, Afungchwi GM, Ladas EJ (2017): A systematic review of integrative clinical trials for supportive care in pediatric oncology: a report from the International Society of Pediatric Oncology, T&CM collaborative. Support Care Cancer. (17 pages). doi:10.1007/s00520-017-3908-0
Rafai P, Papp Z, Jakab L, Tuboly T, Jurkovich V, Brydl E, Ózsvári L, Kósa E (2011): The effect of fermented wheat germ extract on production parameters and immune status of growing pigs. J Anim Feed Sci. 20:36-46.
Rahman M, Hasan MR (2015): Cancer metabolism and drug resistance. Metabolites. 5: 571-600.
Rajasekaran A, Kalaivani M (2013): Designer foods and their benefits: A review. J Food Sci Technol. 50(1):1-16.
Rizzello CG, Nionelli L, Coda R, Di Cagno R, Gobbetti M (2010): Use of sourdough fermented wheat germ for enhancing the nutritional, texture and sensory characteristics of the white bread. Eur Food Res Technol. 230:645–54.
Rizzello CG, Cassone A, Coda R, Gobbetti M (2011): Antifungal activity of sourdough fermented wheat germ used as an ingredient for bread making. Food Chemistry. 127:952-9.
Rizzello CG, Mueller T, Coda R, Reipsch F, Nionelli L, Curiel JA, Gobbetti M (2013): Synthesis of 2-methoxy benzoquinone and 2,6-dimethoxybenzoquinone by selected lactic acid bacteria during sourdough fermentation of wheat germ. Microbial Cell Factories. 12:105.
Saiko P, Ozsvar-Kozma M, Madlener S, Bernhaus A, Lackner A, Grusch M, Horváth Z, Krupitza G, Jaeger W, Ammer K, Fritzer-Szekeres M, Szekeres T (2006): Avemar, a nontoxic fermented wheat germ extract, induces apoptosis and inhibits ribonucleotide reductase in human HL-60 promyelocytic leukemia cells. Cancer Lett. 250:323-8.
Saiko P, Ozsvar-Kozma M, Graser G, Lackner A, Grusch M, Madlener S, Krupitza G, Jaeger W, Hidvégi M, Agarawal RP, Fritzer-Szekeres M, Szekeres T (2009): Avemar, a nontoxic fermented wheat germ extract, attenuates the growth of sensitive and 5-FdUrd/Ara-C cross-resistant H9 human lymphoma cells through induction of apoptosis. Oncol Rep. 21:787-91.
Sarich C (2014): Avemar: Fermented Wheat Germ Kills All Types of Cancer Cells FAST. [online document]. Natural Society.
Sawikowska A (2020): Meta-analysis of flavonoids with antiviral potential against coronavirus. Biometrical Letters. doi:10.2478/bile-2020-0002
Schachter MB (2009): Supporting body defenses against breast cancer with Avemar & AHCC. 8th Annual Complementary Medicine Conference: “A Holistic Approach to Breast Health”: SUNY. New Paltz, NY April 19, 2009.
Schachter MB (2010): Integrative oncology for clinicians and cancer patients. J Orthomol Med. 25(4):169-94.
Seely D, Ennis JK, McDonell E, Zhao L (2018): Naturopathic oncology care for thoracic cancers: A practice. Integr Cancer Ther. 17(3): 793–805.
Selhub EM, Logan AC, Bested AC (2014): Fermented foods, microbiota, and mental health: ancient practice meets nutritional psychiatry. Journal of Physiological Anthropology. 33:2 (12 pages).
Shaw H (2015): Complementary and alternative medicine. In: Oxford American handbook of oncology (2nd edition). Eds. G.H. Lyman, J. Cassidy, D. Bissett, R.A.J. Spence, M. Payne. Oxford University Press, New York, pp. 195-204.
Shiao T-K, Shiao T-K, Shiao JC, Shiao I-S (2010): Successful treatment of chemotherapy-induced alopecia with LaserCap: a case report. Hair Transplant Forum International. September/October 2010, p. 156.
Shibuya N, Inoue K-ich, Tanaka G, Akimoto K, Kubota K (2015): Augmented pentose phosphate pathway plays critical roles in colorectal carcinomas. Oncology. 88:309-19.
Simabuco FM, Morale MG, Pavan ICB, Morelli AP, Silva FR, Tamura RE (2018): p53 and metabolism: from mechanism to therapeutics. Oncotarget. 2018, Vol. 9, (No. 34), pp: 23780-23823.
Smith J (2008): Fermented wheat germ extract beneficial in cancer therapy. Natural News. Oktober 14, 2008.
Soliman MG, Ashry OM, Ahmed MAE, Abd El-Naby YH (2015): Improvement of hematopoietic and immunologic findings in sublethal gamma irradiated rats treated with bone marrow transplantation and wheat germ oil. Journal of Immune Based Therapies, Vaccines and Antimicrobials. 4: 9-18.
Son HJ, Jang YJ, Jung CH, Ahn J, Ha TY (2019): 2,6-Dimethoxy-1,4-benzoquinone Inhibits 3T3-L1 Adipocyte Differentiation via Regulation of AMPK and mTORC1. Planta Med. 85: 210-216.
Song J-H, Kim J-K, Jang H-D (2014): Ferulic acid released by treatment with Aspergillus oryzae contributes to the cellular antioxidant capacity of wheat germ extract. Food Sci Biotechnol. 23:1327-33.
Song Y, Jeong H-Y, Lee J-K, Choi Y-S, Kim D-O, Jang D, Park C-S, Maeng S, Kang H (2019): Enzyme treatment alters the anti-inflammatory activity of the water extract of wheat germ in vitro and in vivo. Nutrients. 2019 Oct; 11(10): 2490. (13 pages).
Stengler M (2013): Simple wheat germ extract revealed to be a powerful cancer fighter. In: Dr. Stengler’s guide to conquering disease. Health Revelations, Baltimore, MD, pp. 3-5; 18.
Stipkovits L, Lapis K, Hidvégi M, Kósa E, Glavits R, Resetár Á (2004): Testing the efficacy of fermented wheat germ extract against mycoplasma gallisepticum infection of chickens. Poultry Sci. 83:1844-8.
Sukkar SG, Cella F, Rovera GM, Nichelatti M, Ragni G, Chiavenna G, Giannoni A, Ronzani G, Ferrari C (2008): A multicentric prospective open trial on the quality of life and oxidative stress in patients affected by advanced head and neck cancer treated with a new benzoquinone-rich product derived from fermented wheat germ (Avemar). Mediterranean J Nutr Metab. 1:37-42.
Sukkar SG, Rossi E, Gradaschi R, Machello N (2018): Avemar, a new benzoquinone containing natural product in SLE patients treatment. XVII Mediterranean Congress of Rheumatology. Abstract OC6:4. Clin Exp Rheumatol. 36, 1, Suppl. 109, 38.
Szende B, Rásó E, Hidvégi M, Tömösközi-Farkas R, Paku S, Prónai L, Bocsi J, Lapis K (1998): Egy új, szubszituált benzokinon tartalmú antimetasztatikus készítmény. Orv Hetil. 139(48):2893-7.
Szende B, Marcsek Z, Kocsis Z, Tompa A (2004): Effect of simultaneous administration of Avemar and cytostatic drugs on viability of cell cultures, growth of experimental tumors, and survival of tumor-bearing mice. Cancer Biother Radiopharm. 19(3):343-9.
Tai C-J, Wang W-C, Wang C-K, Wu C-H, Yang M-D, Chang Y-J, Jian J-Y, Tai C-J (2013): Fermented wheat germ extract (FWGE) induced cell death and enhanced cytotoxicity of cisplatin and 5-fluorouracil on human hepatocellular carcinoma cells. Evid-based Compl Altern Med. Vol. 2013, Article ID 121725, 9 pages.
Tarcsai KR, Kapran I, Hidvégi M, Stercz B, Nagy K, Ongrádi J (2020): Fermentált búzacsíra-kivonat (Avemar) antivirális hatásának vizsgálata macska AIDS modellben. Magyar Állatorvosok Lapja. 142: 731-41.
Tarcsai KR, Hidvégi M, Corolciuc O, Nagy K, Abbas AA, Ablashi DV, Kövesdi V, Ongrádi J (2023): The effects of Avemar treatment on feline immunodeficiency virus infected cell cultures. Vet Med Sci. 9: 1446-1455.
Tejeda M, Gaál D, Szűcs I, Telekes A (2007): Avemar inhibits the growth of mouse and human xenograft mammary carcinomas comparable to endocrine treatments. J Clin Oncol. 25(18):21132.
Telekes A, Hidvégi M (2000): Az Avemar hatásmechanizmusa – rákellenes hatások laboratóriumi állatokban és daganatos betegekben. Nőgyógyászati Onkológia. 5:188-9. Available at: http://hidvegimate.hu/download.php?id=9
Telekes A, Hidvégi M (2001): Az Avemar hatásmódja (2) – immunológiai hatások. Nőgyógyászati Onkológia. 6:40-1. Available at: http://hidvegimate.hu/download.php?id=8
Telekes A, Hidvégi M (2001): Az Avemar hatásmódja (3) – jelátviteli folyamatok és anyagcsere. Nőgyógyászati Onkológia. 6:144-5. Available at: http://hidvegimate.hu/download.php?id=10
Telekes A, Kiss-Tóth E, Nagy T, Qwarnstrom EE, Kúsz E, Polgár T, Resetár Á, Dower SK, Duda E (2005): Synergistic effect of Avemar on proinflammatory cytokine production and Ras-mediated cell activation. Ann N Y Acad Sci. 1051:515–28.
Telekes A, Resetár Á, Bálint G, Blazsó G, Falkay G, Lapis K, Rásó E, Szende B, Ehrenfeld M, Shoenfeld Y, Hidvégi M (2007): Fermented wheat germ extract (Avemar) inhibits adjuvant arthritis. Ann N Y Acad Sci. 1110:348-61.
Telekes A, Rásó E (2007): Changes in the kinase expression panel of K562 human leukemia after Avemar treatment. J Clin Oncol. 25(18):14143.
Telekes A, Hegedűs M, Chae C-H, Vékey K (2009): Avemar (Wheat germ extract) in Cancer Prevention and Treatment. Nutr Cancer. 61(6):891-9.
Tereshina NS, Samylina IA, Kostennikova ZP (2012): Drug fermentation and preparation. Farmaciya. 2012(3): 53-6.
Tömösközi-Farkas R, Daood HG (2004): Modification of chromatographic method for the determination of benzoquinones in cereal products. Chromatographia. 12:227-30.
Tompa A, Kocsis Z, Marcsek Z, Jakab M, Szende B, Hidvégi M (2003): Chemoprevention with Tamoxifen and Avemar by inducing apoptosis on MCF-7 (ER+) Breast cancer cells. In: 2nd Congress of the World Society for Breast Health. Monduzzi Editore, Bologna, p. 61-6.
Traub M (2010): Avemar outshines new cancer ‘breakthrough’ drug. Townsend Letter. 2010 October issue.
Tuscano JM (2017): Treatment of Non-Hodgkin’s Lymphoma: State of the Art and Home Brewed Approaches. 18th Annual Advances in Oncology Conference. September 22-23, 2017, Sacramento CA.
Uğur Y (2014): The Cytotoxic Effects of Wheat Germ Extract on Glioblastoma Cell Line. Other thesis, TED ANKARA KOLEJİ. Available at: http://tedprints.tedankara.k12.tr/562/
Vágner M (2002): A taste of hope. An interview with Mate Hidvegi. New Hungarian Review. 11(1): 18-23.
Verni M, Rizzello CG, Coda R (2019): Fermentation Biotechnology Applied to Cereal Industry By-Products: Nutritional and Functional Insights. Front Nutr. 2019;6:42. 13 p. Published 2019 Apr 12. doi:10.3389/fnut.2019.00042
Vetvicka V, Vetvickova J (2016): Comparison of immunological properties of various bioactive combinations. Part II. Int J Clin Pathol J. 2(5):00053.
Voigt W, Mueller T, Jordan K, Reipisch F, Nerger K, Schmoll HJ (2009): Promising cytotoxic activity profile of fermented wheat germ extract (Avemar) in human cancer cell lines . Eur J Cancer. S7:110.
VRP Staff (2013): The autoimmune/ cardiovascular connection.
Waasiullah M, Yadav P, Yadav S, Mishra P (2023): Role of nutraceutical and herbal adjuvant in the chemotherapy of cancer. World J Pharm Res. 12, 874-887.
Walsh N (2006): Avemar as supportive therapy in cancer. Internal Medicine News. 39(13):35.
Wang C-W, Wang C-K, Chang Y-J, Choong C-Y, Lin C-S, Tai C-J, Tai C-J (2015): Preclinical evaluation on the tumor suppression efficiency and combination drug effects of fermented wheat germ extract in human ovarian carcinoma cells. Evid-based Compl Altern Med. Vol. 2015, Article ID 570785, 8 pages.
Wcislo G, Szarlej-Wcislo K (2014): Colorectal cancer prevention by wheat consumption: A three-valued logic – true, false, or otherwise? In: Wheat and rice in disease prevention and health. Benefits, risks and mechanisms of whole grains in health promotion. Eds. R.R. Watson, V.R. Preedy, S. Zibadi. Elsevier, Academic Press, New York, pp. 91-111.
Weitzen R, Epstein N, Oberman B, Shevetz R, Hidvégi M, Berger R (2021): Fermented wheat germ extract (FWGE) as a treatment additive for castration-resistant prostate cancer: a pilot clinical trial. Nutr Cancer. 2021 Jul 21;1-9. doi:10.1080/01635581.2021.1952457
Whitcomb J (2013): Fermented wheat germ and cancer regulation. [online document].
Williams DG (2005): A cancer therapy out of the blue. Alternatives for the Health Conscious Individual. 11(3):17-24.
Williams DG (2014): How Avemar helps fight cancer. http://www.drdavidwilliams.com/. Available at: http://www.drdavidwilliams.com/avemar-cancer/
Wilson D (2007): Anti-aging and anti-cancer properties of Avemar. Townsend Letter. October issue:101-4.
Winer MC (2012): DCA and Avemar. A theoretical protocol for cancer.
Wright KM (2005): Is it really from heaven above? The cancer miracle that leaves healthy cells healthy. HSI Health Sciences Institute. December issue. (4 pages).
Xie X, Zu X, Laster K, Dong Z, Kim DJ (2021): 2,6-DMBQ suppresses cell proliferation and migration via inhibiting mTOR/AKT and p38 MAPK signaling pathways in NSCLC cells. J Pharmacol Sci. 145:279-288.
Yang M-D, Chang W-S, Tsai C-W, Wang M-F, Chan Y-C, Chan K-C, Lu M-C, Kao A-W, Hsu C-M, Bau D-T (2016): Inhibitory effects of AVEMAR on proliferation and metastasis of oral cancer cells. Nutr Cancer. 68(3): 473-80.
Yeend T, Lockwood C, McArthur A (2012): The effectiveness of Avemar (a fermented wheat germ extract) as an adjunct therapy in the treatment of cancer: A systematic review. (Poster presentation.). The Adelaide University Health Sciences conference.
Yoo A, Jang YJ, Ahn J, Jung CH, Ha TY (2021): 2,6-Dimethoxy-1,4-benzoquinone increases skeletal muscle mass and performance by regulating AKT/mTOR signaling and mitochondrial function. Phytomedicine. 91: 153658 (11 pages).
Yoo J-G, Kim M-D (2010): Production of 2-Methoxy-1,4-benzoquinone (2-MBQ) and 2,6-Dimethoxy-1,4-benzoquinone (2,6-DMBQ) from wheat germ using lactic acid bacteria and yeast. Food Engineering Progress. 14(4):292-8.
Yoo J-G, Kim D-H, Park E-H, Lee J-S, Kim S-Y, Kim M-D (2011): Nuruk, a traditional Korean fermentation starter, contains the bioactive compound 2,6-dimethoxy-1,4-benzoquinone (2,6-DMBQ). J Korean Soc Appl Biol Chem. 54(5):795-8.
Youssef MKE, El-Tellawy FM, El-Melegy NT, Mohamed MMH (2010): Immuno-effect of raw, gamma irradiated, microwave treated and fermented wheat germs in experimental rats. J Food Dairy Sci. 1(1):29-43.
Yusuf OK, Bewaji CO, Ekanem JT (2010): Biochemical evaluation of fermented wheat germ extract on Trypanosoma brucei-infected rats. Afr J Biomed Res. 13:219-24.
Yusuf OK (2010): Evaluation of anti-trypanosomal activities of fermented wheat germ and garlic bulb extracts in T. brucei-infected rats. Thesis submitted to the Department of Biochemistry, University of Ilorin, Ilorin, Nigeria, in partial fulfilment of the requirement for the award of Doctor of Philosophy (Ph.D.) in biochemistry. Ilorin, July, 2010.
Yusuf OK, Ekanem JT (2010): Studies of phytochemical constituents and anti-trypanosomal properties of fermented wheat germ and garlic bulbs extract on Trypanosoma brucei-infected rats. J Med Plants Res. 4(19):2016-20.
Yusuf OK, Bewaji CO (2011): GC-MS of volatile components of fermented wheat germ extract. J Cereals Oilseeds. 2(3): 38-42.
Zalatnai A, Lapis K, Szende B, Rásó E, Telekes A, Resetár Á, Hidvégi M (2001): Wheat germ extract inhibits experimental colon carcinogenesis in F-344 rats. Carcinogenesis. 22(10):1649-52.
Zhang J, Xiao X, Dong Y, Wu J, Yao F, Zhou X (2015): Effect of Fermented Wheat Germ Extract with Lactobacillus plantarum dy-1 on HT-29 Cell Proliferation and Apoptosis. J. Agric. Food Chem., Just Accepted Manuscript. Publication Date (Web): February 6, 2015. doi:10.1021/acs.jafc.5b00041
Zhang J, Xiao X, Dong Y, Wu J, Zhou X (2015): Antitumor activities and apoptosis-regulated mechanisms of fermented wheat germ extract in the transplantation tumor model of human HT-29 cells in nude mice. Biomed Environ Sci. 28(10): 718-27.
Zhurakivska K, Troiano G, Caponio VCA, Dioguardi M, Arena C, Muzio LL (2018): The Effects of Adjuvant Fermented Wheat Germ Extract on Cancer Cell Lines: A Systematic Review. Nutrients. 10:1546.
Zsila F (2014): Complementary alternative medicine: fermented wheat germ extract. [online document]. Drugdiscovery.com.
Zu X, Ma X, Xie X, Lu B, Laster K, Liu K, Dong Z, Kim DJ (2020): 2,6-DMBQ is a novel mTOR inhibitor that reduces gastric cancer growth in vitro and in vivo. J Exp Clin Cancer Res. 39:107 (14 pages).